The 1st Central European Conference "Chemistry towards Biology"
is organised by the Slovenian Chemical Society in collaboration
with National Institute of Chemistry, Ljubljana, University of
Ljubljana. Faculty for Chemistry and Chemical Technology, and
Universty of Trieste. It is supported by me Slovenian Ministry
of Education, Science, and Sport and the Federation of European
Chemical Societies (event number 267).
| Sunday, 8 September 2002 |
| Tutorial lectures |
| 15:00 |
Ivano Bertini |
Tutorial on biological NMR |
| 15:50 |
Dušan Turk |
Macromolecular X-ray crystallography: driven by automation and/or biology |
| 16:40 |
Janez Mavri |
Biomolecular simulation: A challenge for 21th Century |
| 17:30 |
BREAK |
| Opening |
| 18:00 |
Official openning |
| Sunset lecture |
| 18:30 |
Børge Diderichsen |
Bringing chemistry to life |
| Get-together party |
| 19:30 - |
|
| Monday, 9 September 2002 |
| Plenary lecture (Chairman: L. Randaccio) |
| 9:00 |
Louise N. Johnson |
Protein kinases: structural basis of substrate specificity and control |
| Session lectures |
| 10:00 |
Peter Laggner |
Biomimetic reactions with liposomes in bulk and at solid surfaces |
| 10:30 |
Christoph Kratky |
Structure and mechanism of hydroxinitrile lyases |
| 11:00 |
COFFEE BREAK |
| 11:20 |
Ettore Benedetti |
The use of non coded aminoacid residues in drug design |
| 11:50 |
Enrico Rizzarelli |
Interactions of copper(II) with fragments of proteins involved in conformation diseases |
| 12:20 |
Krzysztof Lewinski |
title will be announced later |
| 12:50 |
LUNCH |
| Plenary lecture (Chairman: B. Kamenar) |
| 15:00 |
John R. Helliwell |
The intersection of the frontiers of structural chemistry and structural biology |
| Session lectures |
| 16:00 |
Anna Tramontano |
Frontiers of protein structure prediction |
| 16:30 |
Mariusz Jaskolski |
Protein structure at atomic resolution |
| 17:00 |
COFFEE BREAK |
| 17:20 |
Martino Bolognesi |
Protein crystallograpliy in the structural genomic era |
| 17:50 |
Alojz Demšar |
Observation of carboxylate shift dynamics in zinc carboxylate complexes by VT NMR |
| 18:20 |
Tamara Lah |
Biochemistry towards tumour biology |
| Tuesday, 10 September 2002 |
| Plenary lecture (Chairman: J. Mavri) |
| 9:00 |
Bernard Meunier |
The chemical design of new antimalarial agents based on mechanistic studies |
| Session lectures |
| 10:00 |
Andras Perczel |
Ab initio computed properties of major and minor secondary structure elements of proteins |
| 10:30 |
Michal K. Cyranski |
Aromaticity of biologically active systems |
| 11:00 |
COFFEE BREAK |
| 11:20 |
Vilim Šimanek |
Chemical features of quaternary benzo[c]phenantridine alkaloids affecting their biological activities |
| 11:50 |
Vladimir Kren |
Aminosugars as ligands of activating receptor of natural killer (NK) cells:
A strategy from ligand optimization to development of glycodrug for in vivo application
|
| Organized Trip |
| Wednesday, 11 September 2002 |
| Plenary lecture (Chairman: B. Stanovnik) |
| 9:00 |
Rowena G. Matthews |
Cobalamin-dependent and cobalamin-independent methionine synthases: ls there more than one way to skin a cat? |
| Session lectures |
| 10:00 |
Bernard Kräutler |
Bioorganometallic chemistry of B12 |
| 10:30 |
Ivana Weygand-Djurašević |
Fidelity of decoding by aminoacyl-tRNA synthethases |
| 11:00 |
COFFEE BREAK |
| 11:20 |
Marija Abramić |
Extracellular lipase from streptomyces rimosus: An unusual bacterial lipolytic enzyme |
| 11:50 |
Marie Stiborova |
A novel mechanism of anticancer effect of a chemotherapeutic, ellipticine: Chemical research explains its selective pharmacological efficiency |
| 12:20 |
György M. Keserű |
Preparative and theoretical models of cytochrome P450 catalyzed oxidative metabolism |
| 12:50 |
LUNCH |
| Plenary lecture (Chairman: Z. Maksić) |
| 15:00 |
Pavel Hobza |
Structure and dynamic of the nucleic acid base pairs: Ab initio calculations and molecular dynamics simulations |
| Session lectures |
| 16:00 |
Igor Tvaroška |
Toward an understanding of the catalytic mechanism of glycosyltransferases. Ab initio MO study |
| 16:30 |
Renee Schröder |
RNA chaperone StpA induces structural changes in essential base triples of the td group I intron |
| 17:00 |
Katalin Kövér |
Dynamic properties of biomolecules studied by NMR relaxation and diffusion measurements |
| Poster session |
| 17:30 - 19:00 |
|
| Thursday, 12 September 2002 |
| Plenary lecture (Chairman: I. Bertini) |
| 9:00 |
Claudio Luchinat |
Metal cofactors in biology |
| Session lectures |
| 10:00 |
Branko Stanovnik |
β-dimetylamino—α,β-didehydro-α-amino acids and their chiral analogs
in the synthesis of applysinopsins and analogs and some other biologically active chiral
α-heteroaryl-α-amino acids |
| 10:30 |
Silvio Aime |
Paramagnetic lanthanide(III) complexes in MRI: From extracellular contast agents to probes in molecular imaging |
| 11:00 |
COFFEE BREAK |
| 11:20 |
Gorazd Vesnaver |
Specific binding of the minor groove directed ligands distamaycin A and netropsin to
the 17-mer DNA duplexes containing one 5AT and one 4ATGC binding site: Calorimetric and spectroscopic studies |
| 11:50 |
Henriette Molinari |
Structural and folding studies on lipocalins: Beta-lactoglobulins and chicken liver basic fatty acid binding protein |
| 12:20 |
Janez Plavec |
NMR solution structure of a novel bimolecular G—quadruplex fold of d(G4T4G3)2 |
| 12:50 |
LUNCH |
| Plenary lecture (Chairman: P. Laggner) |
| 15:00 |
Ada E. Yonath |
Antibiotics targeting ribosomes |
| 16:00 |
COFFEE BREAK |
| Perspectives lectures |
| 16:15 |
Peter Schuster |
Diversity and plasticity of RNA. Beyond the one sequence — one structure paradigm |
| 17:00 |
Boštjan Kobe |
Protein regulation, protein-protein interactions and structural genomics |
| 17:45 |
László Patthy |
Drug target selection and drug development in the post-genome era |
| Banquet |
| 20:00- |
|